Does MS Cause Weight Loss?

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Multiple sclerosis (MS) is a chronic disease that can affect many parts of life, including fatigue, mobility and mood. A common question is whether MS causes weight loss.

MS does not directly cause weight loss in most people. Many people with MS actually find weight gain harder to avoid, because fatigue and mobility problems can limit activity.

Unintended weight loss can still happen, usually because of swallowing problems, depression, fatigue, advanced disability or medicine side effects. This article explains those causes and what can help.

Definition Of Multiple Sclerosis

Multiple sclerosis is a disease of the central nervous system, the brain and spinal cord. According to MedlinePlus, MS damages myelin, the protective coating around nerve cells, which disrupts signals between the brain and the body.

No two cases are the same. MS is two to three times more common in women than men, and it most often begins between ages 20 and 40.

There is no cure, but disease-modifying treatments can reduce relapses and slow progression, and other treatments help manage symptoms.

Symptoms Of MS

Symptoms vary from person to person, but commonly include:

  • Fatigue, muscle weakness, stiffness or spasms;
  • Numbness or tingling;
  • Bladder control problems;
  • Vision problems, such as double vision or eye pain;
  • Trouble with coordination, walking or balance;
  • Thinking or memory difficulties.

Other symptoms can include dizziness, mood changes, depression, pain and swallowing problems.

Doctors diagnose MS using a neurological exam, MRI scans and sometimes a spinal fluid test or evoked potential tests. If you notice new neurological symptoms, see a doctor promptly.

Relationship Between MS And Weight Loss

Research does not show that MS itself burns calories or causes weight loss. Weight changes in MS usually come from how symptoms affect eating and activity.

Possible factorLikely effect on weight
Swallowing problems (dysphagia)Can lead to weight loss and malnutrition
Advanced disabilityHigher risk of weight loss and muscle loss
Depression or fatigueCan reduce appetite or the ability to shop and cook
Lower activityOften leads to weight gain
Steroid treatment for relapsesOften increases appetite and weight

A 2020 review notes that swallowing problems are common in MS and that dysphagia may lead to a high risk of malnutrition, weight loss and dehydration. They are more frequent in advanced disease.

Unintended weight loss is a sign to talk with your care team. It may come from MS, a medicine or a separate health problem that needs checking.

Possible Reasons For Weight Loss In MS Patients

When weight loss happens in MS, the cause is usually one of the following. Unlike intentional weight loss, it is not a goal to pursue.

  1. Swallowing Problems: Dysphagia can make eating slow, tiring or unsafe, so people eat less. It also raises the risk of choking and pneumonia.
  2. Fatigue and Mobility Problems: Fatigue is one of the most common MS symptoms. It can make shopping, cooking and eating harder.
  3. Depression and Anxiety: Depression is common in MS and can reduce appetite and interest in food.
  4. Medication Side Effects: Some medicines used in MS can cause nausea, diarrhea or reduced appetite. Talk to your doctor before stopping any medicine.
  5. Advanced Disability and Muscle Loss: People with more severe disability are more likely to lose muscle and weight.

Each person's situation is different, so the cause needs to be identified before choosing treatment.

Diagnosis Of Weight Loss In MS Patients

Unintended weight loss should be checked by a healthcare provider, not assumed to be "just MS." Learn more about ways in which clinicians can diagnose weight loss and its causes.

Your provider will ask when the weight loss started, how much you have lost, how you are eating and swallowing, and what medicines you take. Other conditions, such as thyroid problems, diabetes or cancer, also need to be ruled out.

AssessmentDescription
Physical ExaminationChecks weight, vital signs and signs of muscle loss.
Medical TestsBlood tests can check thyroid function, blood sugar, nutrition markers and other causes of weight loss.
Swallowing EvaluationA speech-language pathologist can test how safely and efficiently you swallow.
Nutritional AssessmentA dietitian reviews your eating habits and nutrition needs.
Mood ScreeningChecks for depression or anxiety that may affect appetite.

Finding the cause makes it possible to choose the right treatment.

Treatments For Weight Loss In MS Patients

Treatment depends on the cause. A team approach often works best, including your neurologist, a dietitian, a speech-language pathologist and a physical therapist.

For swallowing problems, swallowing therapy, changes in posture and modified food textures can make eating safer. A dietitian can help you get enough calories and protein, sometimes with nutrition drinks.

Physical activity tailored to your abilities, especially strength training, helps maintain muscle. Swimming or yoga can be good low-impact options.

Some people with MS have the opposite concern and want to lose weight. For them, the same approaches used by others apply, such as diet plans focused on nutrient-rich meals and appropriate exercise. With the right support, successful weight loss management is possible either way.

Impact Of Weight Loss On Quality Of Life

Unintended weight loss can have a significant impact on physical, emotional and social well-being.

  • Physical: Losing muscle can increase weakness, fatigue and the risk of falls, and make daily tasks such as dressing or bathing harder. Poor nutrition can also slow healing and weaken immunity.
  • Psychological: Unintended weight loss can add to anxiety, depression and body image concerns, especially when eating becomes difficult.
  • Social: Swallowing problems can make eating out with friends stressful, which can lead to isolation.

Maintaining muscle through exercise, eating enough nutrient-rich food and getting support from your care team and community can help protect quality of life.

Frequently Asked Questions

What Types Of Exercise Can Be Beneficial For MS Patients Experiencing Weight Loss?

Strength training helps rebuild and protect muscle, which matters most when weight loss comes from muscle wasting.

Aerobic exercise such as walking, swimming or cycling and flexibility work such as yoga or tai chi also help. A physical therapist can tailor a plan to your abilities and fatigue.

Are There Any Dietary Changes That Can Help With Weight Loss In MS Patients?

If you are losing weight you didn't intend to, the goal is to eat enough: regular meals, protein at each meal and energy-dense foods such as nuts, nut butters and whole-milk dairy.

A registered dietitian can help, and a speech-language pathologist can suggest food textures if swallowing is hard.

Are There Any Lifestyle Modifications That Can Help Manage Weight Loss In MS Patients?

Plan meals for times when your energy is best, use easy-to-prepare foods, eat smaller meals more often, and ask for help with shopping and cooking.

Treating depression and managing fatigue can also improve appetite and support optimal health.

Are There Any Medications Available That Can Help With Weight Loss In MS Patients?

For unintended weight loss, treatment targets the cause, such as swallowing therapy, treatment for depression or a change in a medicine causing side effects.

For people with MS who have overweight or obesity, the same FDA-approved weight-management drugs used by others may be options under a doctor's care. Your neurologist should be involved in any decision.

Are There Any Natural Remedies That Can Help With Weight Loss In MS Patients?

No herbal remedy or supplement is proven to treat MS-related weight changes. A balanced diet, regular activity and good sleep help.

Limiting unhealthy fats and added sugars supports overall health. Check with your doctor before taking any supplement, since some can interact with MS medicines.

Conclusion

MS does not directly cause weight loss in most people, and weight gain is often the bigger challenge. When unintended weight loss happens, swallowing problems, depression, fatigue, advanced disability or medicine side effects are usually involved.

Tell your care team about any unexplained weight loss so the cause can be found and treated. Strength training, enough protein and calories, and help with swallowing can make sure your body stays strong.

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